Search results for “Fundamentals of clinical trials”

Fundamentals of Clinical TrialsThis is the fifth edition of a very successful textbook on clinical trials methodology, written by recognized leaders who have long and extensive experience in all areas of clinical trials. The three authors of the first four editions have been joined by two others who add great expertise. A chapter on regulatory issues has been included and the chapter on data monitoring has been split into two and expanded. Many contemporary clinical trial examples have been added. There is much new material …

Fundamentals of Clinical TrialsThe randomized control clinical trial has become the gold standard scientific method for the evaluation of pharmaceuticals, biologics, devices, procedures and diagnostic tests. This trial design has been successfully used in both therapeutic and disease prevention trials. It is superior to alternative designs by eliminating several sources of bias which exist in those designs. This role has evolved over the past three decades in a number of disease areas including cardiology, opthalmology, cance…

Fundamentals of Clinical TrialsThis book addresses the fundamentals of randomized control clinical trials, devoting a chapter to each of the critical areas of a protocol. The new edition is revised and expanded, with the number of examples illustrating the fundamentals considerably increased….

Dental Pulp Tissue Regeneration, a Promising Future: Concepts, Trends and In Vitro & Pre-clinical Trials of Fundamental Tissue Engineering Principles of Pulp RegenerationThe trend for the future of Root Canal Therapy is leaning towards dental pulp tissue regeneration using tissue engineering principles, stem cells, growth factors and scaffolds. Ideally, Root Canal Therapy would involve the removal of diseased pulp tissue and its permanent replacement with healthy pulp to revitalize teeth. Traditionally, during a Root Canal Therapy, the diseased pulp has been removed and replaced by a biocompatible synthetic material. This book presents the concepts and founda…

Fundamentals of Clinical TrialsThe trend for the future of Root Canal Therapy is leaning towards dental pulp tissue regeneration using tissue engineering principles, stem cells, growth factors and scaffolds. Ideally, Root Canal Therapy would involve the removal of diseased pulp tissue and its permanent replacement with healthy pulp to revitalize teeth. Traditionally, during a Root Canal Therapy, the diseased pulp has been removed and replaced by a biocompatible synthetic material. This book presents the concepts and founda…

An Overview of Clinical Trial Operation: Fundamentals of clinical trial planning and management in drug developmentAt the moment, clinical trial is the most relevant method at our disposal to explore and establish safety/efficacy of a new medicine. It is the fundamental basis of clinical development programs of healthcare products. Clinical research has opened up several new career choices. Graduates in medicine, pharmacy and other life sciences now have the option to work as investigators, scientists, project managers, data managers, monitors, study coordinators, regulatory affairs managers, and so on. Many…

Designing Clinical ResearchDesigning Clinical Research has been extensively revised and continues to set the standard as a practical guide for doctors, nurses, pharmacists, and other health professionals involved in all forms of clinical, translational, and public health research. It presents advanced epidemiologic concepts in a reader-friendly way, and suggests common sense approaches to the challenging judgments involved in designing, funding, and implementing. New to this edition: Expanded and updated content in ev…

Fundamentals of Clinical Trials 3rd (third) Edition by Lawrence M. Friedman, Curt D. Furberg, David L. DeMets published by Springer (1998)Designing Clinical Research has been extensively revised and continues to set the standard as a practical guide for doctors, nurses, pharmacists, and other health professionals involved in all forms of clinical, translational, and public health research. It presents advanced epidemiologic concepts in a reader-friendly way, and suggests common sense approaches to the challenging judgments involved in designing, funding, and implementing. New to this edition: Expanded and updated content in ev…

Multiple Analyses in Clinical Trials: Fundamentals for Investigators (Statistics for Biology and Health)Concentrating on the rationale for the analyses, the difficulties posed by their interpretation, easily understood solutions, and useful problem sets, this book will help clinical investigators understand multiple analysis procedures and key issues. It is written for advanced medical students, clinical investigators at all levels, research groups within the pharmaceutical industry, regulators at the local, state, and federal level, and biostatisticians….