Search results for “Biostatistics experimental design and statistical inference”

Biostatistics: Experimental Design and Statistical InferenceThis textbook takes a unique approach to explaining and demonstrating how to use and interpret statistics for the physiological, medical, and life sciences. The first third of the book presents an integrated overview and introduction to experimental design and statistical inference. The rest of the book provides an extensively cross-referenced set of 100 brief critiques of sample case studies embodying all the most common statistical errors or design problems found in the biological literature. …

The Design and Statistical Analysis of Animal ExperimentsWritten for animal researchers, this book provides a comprehensive guide to the design and statistical analysis of animal experiments. It has long been recognised that the proper implementation of these techniques helps reduce the number of animals needed. By using real-life examples to make them more accessible, this book explains the statistical tools employed by practitioners. A wide range of design types are considered, including block, factorial, nested, cross-over, dose-escalation and repe…

DNA Methylation Microarrays: Experimental Design and Statistical Analysis (Chapman & Hall/CRC Biostatistics Series)Providing an interface between dry-bench bioinformaticians and wet-lab biologists, DNA Methylation Microarrays: Experimental Design and Statistical Analysis presents the statistical methods and tools to analyze high-throughput epigenomic data, in particular, DNA methylation microarray data. Since these microarrays share the same underlying principles as gene expression microarrays, many of the analyses in the text also apply to microarray-based gene expression and histone modification (ChIP-on-c…

Case-Control Studies: Design, Conduct, Analysis (Monographs in Epidemiology and Biostatistics)Providing an interface between dry-bench bioinformaticians and wet-lab biologists, DNA Methylation Microarrays: Experimental Design and Statistical Analysis presents the statistical methods and tools to analyze high-throughput epigenomic data, in particular, DNA methylation microarray data. Since these microarrays share the same underlying principles as gene expression microarrays, many of the analyses in the text also apply to microarray-based gene expression and histone modification (ChIP-on-c…

Pharmaceutical Experimental Design (Drugs and the Pharmaceutical Sciences)This useful reference describes the statistical planning and design of pharmaceutical experiments, covering all stages in the development process-including preformulation, formulation, process study and optimization, scale-up, and robust process and formulation development.Shows how to overcome pharmaceutical, technological, and economic constraints on experiment design!Directly comparing the advantages and disadvantages of specific techniques, Pharmaceutical Experimental Design· offers broad…

Design and Analysis of Ecological ExperimentsEcological research and the way that ecologists use statistics continues to change rapidly. This second edition of the best-selling Design and Analysis of Ecological Experiments leads these trends with an update of this now-standard reference book, with a discussion of the latest developments in experimental ecology and statistical practice.The goal of this volume is to encourage the correct use of some of the more well known statistical techniques and to make some of the less well known but po…

Design and Analysis of Experiments in the Health SciencesAn accessible and practical approach to the design and analysis of experiments in the health sciences Design and Analysis of Experiments in the Health Sciences provides a balanced presentation of design and analysis issues relating to data in the health sciences and emphasizes new research areas, the crucial topic of clinical trials, and state-of-the- art applications. Advancing the idea that design drives analysis and analysis reveals the design, the book clearly explains how to apply design an…

Biostatistics DecodedStudy design and statistical methodology are two important concerns for the clinical researcher. This book sets out to address both issues in a clear and concise manner. The presentation of statistical theory starts from basic concepts, such as the properties of means and variances, the properties of the Normal distribution and the Central Limit Theorem and leads to more advanced topics such as maximum likelihood estimation, inverse variance and stepwise regression as well as, time-to-event, and…

Design of Observational Studies (Springer Series in Statistics)An observational study is an empiric investigation of effects caused by treatments when randomized experimentation is unethical or infeasible. Observational studies are common in most fields that study the effects of treatments on people, including medicine, economics, epidemiology, education, psychology, political science and sociology. The quality and strength of evidence provided by an observational study is determined largely by its design. Design of Observational Studies is both an introduc…